3-Nitro-o-Xylene: Introduction
- 3-nitro-o-xylene is a clear yellow colored liquid with characteristic odor. It is insoluble in water. 3-nitro-o-xylene is stable under recommended storage conditions. Moreover, it produces toxic fumes upon decomposition on heating.
- 3-Nitro-o-xylene is primarily utilized as a chemical intermediate in the production of anti-inflammatory analgesic mefenamic acid. This mefenamic acid is extensively employed in the pharmaceutical industry to decrease inflammation. Additionally, mefenamic acid is also used to treat menstrual pain.
- Heating of 3-nitro-o-xylene releases hazardous products under fire conditions such as carbon oxides and nitrogen oxides (NOx). Furthermore, its handling require extensive care at the time of transportation, which in turn is likely to hamper the market in the near future.
- Based on application, the global 3-nitro-o-xylene market can be segmented into chemical synthesis, dyes, agrochemicals, pharmaceutical, and others. Chemical synthesis and pharmaceutical segments are expected to hold a major share of the global 3-nitro-o-xylene market. Chemical synthesis includes the use of 3-nitro-o-xylene in Michael addition, reduction, henry reaction (nitro-aldol reaction), NEF reaction, o-alkylation, and cyclo-addition. Growing need for intermediates from pharmaceutical sector is expected to boost consumption of 3-nitro-o-xylene in the near future.
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Rising demand for 3-Nitro-o-Xylene from Chemical Synthesis and Pharmaceutical Industry
- 3-nitro-o-xylene is predominantly employed in the pharmaceutical industry. Increase in public and private investment in the healthcare sector is estimated to drive the demand for 3-nitro-o-xylene in pharmaceutical applications in the near future. Furthermore, rise in FDI inflow in developing countries, such as India, is expected to drive the demand for medicines in the near future. For instance, in India, the FDI inflow of US$ 16.50 Bn was obtained for the drugs and pharmaceuticals sector. The inflow was between April 2000 and March 2020. The data is based on the Department for Promotion of Industry and Internal Trade (DPIIT). 3-nitro-o-xylene acts as a natural precursor to a varied range of chemical reaction due to its structure; therefore, its application in the production of pharmaceutical intermediaries and mixtures is likely to increase considerably in the near future.
- The chemical industry offers lucrative opportunities for the application of 3-nitro-o-xylene. 3-nitro-o-xylene has one or more nitrogen dioxide groups bonded by nitrogen to the carbon framework. This bonding leads to versatility and basicity of the 3-nitro-o-xylene. Hence, it is widely used in chemical synthesis.
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Impact of COVID-19 on Global 3-Nitro-o-Xylene Market
- Global spread of the pandemic have severely affected the production of 3-nitro-o-xylene. Declining demand coupled with variation in production of chemicals has led to volatility in pricing of 3-nitro-o-xylene. This, in turn, is likely to negatively affect the market on a temporary basis.
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Asia Pacific to Hold Major Share of Global 3-Nitro-o-Xylene Market
- In terms of region, the global 3-nitro-o-xylene market can be split into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa
- Asia Pacific is estimated to hold a significant share of the global of 3-nitro-o-xylene market. Expansion of the market in the region can be ascribed to an increase in the demand for 3-nitro-o-xylene from pharmaceutical, chemical synthesis, and agrochemical applications.
- Requirement for high-quality materials with excellent efficiency levels has led to the development of new technologies in North America. Manufacturers based in North America have been trying to develop technologies for simple, flexible, and low-cost production of 3-nitro-o-xylene.
- Demand for 3-nitro-o-xylene is likely to increase across Europe in the next few years. The trend is expected to continue in the near future. Upcoming projects in the chemical and pharmaceutical industry are projected to propel the demand for 3-nitro-o-xylene in the region during the forecast period.
- Middle East & Africa and Latin America are likely to account for relatively minor share of the global 3-nitro-o-xylene market. Low share held by these regions is due to unstable political environment and high price of 3-nitro-o-xylene. However, significant demand for 3-nitro-o-xylene in agrochemicals in Latin America is likely to propel the 3-nitro-o-xylene market in the region in the near future.