Crisnuo 2% Crisaborole Ointment

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Crisaborole is the active ingredient in a topical ointment used to treat mild to moderate atopic dermatitis. Crisaborole 2% ointment, sold under the brand name Eucrisa, contains 2% w/w crisaborole as the pharmacologically active component.

Crisaborole is a non-steroidal phosphodiesterase-4 (PDE-4) inhibitor. PDE-4 is an enzyme that breaks down cyclic adenosine monophosphate (cAMP) in immune cells. cAMP is a signaling molecule that regulates inflammatory responses. By inhibiting PDE-4, crisaborole increases cAMP levels, reducing inflammatory cytokine production and relieving atopic dermatitis symptoms.

What Are the Benefits of Using Crisaborole?

Crisaborole offers certain advantages over other eczema treatments:

• Steroid-free - Crisaborole manages inflammation without steroids' side effects.
• Fast-acting - Crisaborole provides quick relief within days.
• Safe for long-term use - Patients can use crisaborole daily for up to a year.
• Well-tolerated - Most patients have no issues with burning or stinging.
• Easy to use - Crisaborole comes in an easy-to-apply ointment.
• Effective - Studies show crisaborole significantly improves eczema symptoms.

By controlling flare-ups and reducing the need for steroids, crisaborole can be an important medication for atopic dermatitis patients.

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